Laboratory Diagnosis of Congenital Toxoplasmosis

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Laboratory Diagnosis of Congenital Toxoplasmosis

Recent studies have demonstrated that screening and treatment for toxoplasmosis during gestation result in a decrease of vertical transmission and clinical sequelae. Early treatment was associated with improved outcomes. Thus, laboratory methods should aim for early identification of infants with congenital toxoplasmosis (CT). Diagnostic approaches should include, at least, detection of Toxopla...

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The laboratory diagnosis of toxoplasmosis.

A case of congenital toxoplasmosis has recently been seen in this hospital The patient, a girl aged 5 years, presented with hydrocephalus, bilateral pes cavus, and blindness. The eyes showed extensive retinochoroiditis thought to be characteristic of toxoplasmosis. Radiographs of the skull showed areas of cerebral calcification. Two years before the birth of the patient the mother had suffered ...

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Serological diagnosis of congenital toxoplasmosis.

A comparison of the indirect haemagglutination test (IHAT) with the dye test (DT) in 23 infants with congenital toxoplasmosis showed that in the early part of the first year of life the IHAT titres were nearly all lower than the DT titres. In six cases the IHAT was negative or the titre was so low that the cases could have been missed in routine screening. Later in the first year the IHAT titre...

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Optimizing the parasitological diagnosis of congenital toxoplasmosis

Early diagnosis of Congenital Toxoplasmosis is highly important, since it can make the treatment possible and reduces sequela for the infant. Serological diagnosis alone cannot be accurate when it does not identify the IgA, IgM or IgG antibodies of low avidity, which do not cross the placent barrier. Therefore, parasitemic identification is important to be carried out by demonstrating the paras...

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Diagnosis of congenital syphilis and toxoplasmosis

transmission of HIV. Cochrane Database Syst. Rev. CD011323. doi:10.1002/ 14651858.CD011323 15. Jamieson, D.J. et al. (2012) Maternal and infant antiretroviral regimens to prevent postnatal HIV-1 transmission: 48-week follow-up of the BAN randomised controlled trial. Lancet 379, 2449–2458. doi:10.1016/S0140-6736(12)60321-3 16. TheKeshoBoraStudyGroup.deVincenzi, I. (2011) Triple antiretroviral co...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2016

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.00487-16